MAC-545496 is a nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR). MAC-545496 displays strong binding affinity to the full-length GraR protein (Kd 0.1 nM). MAC-545496 is an antivirulence agent that reverses beta-lactam resistance in Methicillin-resistant strains (MRSA)[1].
Molecular Weight:
419.89
Purity:
98.01
CAS Number:
[838810-96-1]
Formula:
C18H18ClN5O3S
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound1
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