EGFR-IN-11 is a fourth-generation EGFR-tyrosine kinase inhibitor (EGFR-TKI) with an IC50 of 18 nM for triple mutant EGFRL858R/T790M/C797S. EGFR-IN-11 significantly suppresses the EGFR phosphorylation, induce the apoptosis, and arrest cell cycle at G0/G1[1].
Molecular Weight:
573.71
Purity:
99.30
CAS Number:
[2463200-44-2]
Formula:
C29H35N9O2S
Target:
Apoptosis,EGFR
Application Notes:
MCE Product type: Reference compound1
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