LT052 is a highly selective BET BD1 inhibitor with an IC50 of 87.7 nM. LT052 exhibits nanomolar BRD4 BD1 potency and 138-fold selectivity over BRD4 BD2 (IC50=12.130 µM). LT052 has anti-inflammatory activity and can be used for acute gout arthritis research[1].
Molecular Weight:
449.48
Purity:
98.77
CAS Number:
[2543545-44-2]
Formula:
C22H19N5O4S
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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