Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 µM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1].
Molecular Weight:
324.37
Purity:
98.99
CAS Number:
[20784-50-3]
Formula:
C20H20O4
Target:
Akt,Apoptosis,Autophagy,Reactive Oxygen Species (ROS)
Application Notes:
Natural Products
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