Cenisertib (AS-703569) is an ATP-competitive multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3. Cenisertib induces major growth-inhibitory effects by blocking the activity of several different molecular targets in neoplastic mast cells (MC). Cenisertib inhibits tumor growth in xenograft models of pancreatic, breast, colon, ovarian, and lung tumors and leukemia[1][2][3].
Molecular Weight:
451.54
Purity:
99.86
CAS Number:
[871357-89-0]
Formula:
C24H30FN7O
Target:
Akt,Aurora Kinase,Bcr-Abl,FLT3,STAT
Application Notes:
MCE Product type: Reference compound1
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