K-252d is an indolocarbazole alkaloid found in Nocardiopsis. It is a PKC inhibitor that inhibits PKC isolated from rat brain (IC50=350 nM). It also inhibits calcium- and calmodulin-dependent phosphodiesterase isolated from bovine heart (IC50=46.2 µM).
Molecular Weight:
457.48
CAS Number:
[105114-22-5]
Formula:
C26H23N3O5
Target:
Phosphodiesterase (PDE),PKC
Application Notes:
MCE Product type: Natural Products
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