HS-27, a fluorescently-tethered Hsp90 inhibitor, assays surface Hsp90 expression on intact tissue specimens. HS-27 is made up of the core elements of SNX-5422, an Hsp90 inhibitor, tethered via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC), that binds to ectopically expressed Hsp90. HS-27 has potential use in a see-and-treat paradigm in breast cancer[1].
Molecular Weight:
993.13
Purity:
98.48
CAS Number:
[1562024-11-6]
Formula:
C52H60N6O12S
Target:
HSP
Application Notes:
MCE Product type: Reference compound
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