PF 03716556 is a potent, selective, competitive and reversible acid pump (H+,K+-ATPase) antagonist with pIC50s of 6.026, 6.038 and 6.009 for porcine, canine, and human recombinant gastric H+,K+-ATPase, respectively. PF 03716556 is inactive against other receptors, ion channels, and enzymes. PF 03716556 has the potential for gastroesophageal reflux disease research[1].
Molecular Weight:
394.47
Purity:
99.10
CAS Number:
[928774-43-0]
Formula:
C22H26N4O3
Target:
Proton Pump
Application Notes:
Reference compound
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