RIPK3-IN-1 is a RIPK3 type II DFG-out inhibitor with an IC50 of 9.1 nM. RIPK3-IN-1 inhibits RIPK1 and RIPK2 with IC50s of 5.5 and >10 µM. RIPK3-IN-1 is also a c-Met kinase inhibitor with an IC50 of 1.1 µM[1].
Molecular Weight:
512.53
Purity:
99.30
CAS Number:
[2361139-70-8]
Formula:
C29H25FN4O4
Target:
RIP kinase
Application Notes:
Reference compound
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