PROTAC BRD4 Degrader-6, CAS [[2410947-56-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-131203
Supplier Catalog Number:
HY-131203
Alternative Catalog Number:
MCE-HY-131203-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PROTAC BRD4 Degrader-6 (compound 32a) is a potent small-molecule BRD4PROTAC degrader with IC50 value of 2.7 nM for BRD4 BD1. PROTAC BRD4 Degrader-6 potently degrades BRD4 protein and inhibits the expression of c-Myc. PROTAC BRD4 Degrader-6 inhibits the proliferation of pancreatic cancer cell line BxPC3 and induces apoptosis. PROTAC BRD4 Degrader-6 can be used for human pancreatic cancer research (Pink: Mivebresib (HY-100015), Black: linker, Azido-PEG1-CH2CO2H (HY-108369), Blue: Lenalidomide (HY-A0003))[1].