Gefitinib impurity 1 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2].
Molecular Weight:
321.33
Purity:
99.59
CAS Number:
[675126-26-8]
Formula:
C15H19N3O5
Target:
Drug Metabolite
Application Notes:
MCE Product type: Reference compound1
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