SP-96 is a highly potent, selective and non-ATP-competitive Aurora B (IC50=0.316 nM) inhibitor and shows >2000 fold selectivity against FLT3 and KIT. SP-96 shows selective growth inhibition in NCI60 screening, incluing MDA-MD-468 (GI50=107 nM). SP-96 can be used for the research of triple negative breast cancer (TNBC)[1].
Molecular Weight:
453.47
Purity:
99.65
CAS Number:
[2682114-54-9]
Formula:
C25H20FN7O
Target:
Aurora Kinase
Application Notes:
MCE Product type: Reference compound
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