LXE408 is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 has an IC50 of 0.04 µM for L. donovani proteasome and an EC50 of 0.04 µM for L. donovani. LXE408 has a low propensity to cross the blood brain barrier. LXE408 has the potential for visceral leishmaniasis (VL) research[1].
Molecular Weight:
443.43
Purity:
99.75
CAS Number:
[1799330-15-6]
Formula:
C23H18FN7O2
Target:
Parasite,Proteasome
Application Notes:
MCE Product type: Reference compound
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