3,7-Dihydroxyflavone (Resogalangin) is a flavonoid phytoestrogen, which can be isolated from Adenophora species. 3,7-Dihydroxyflavone is a modulator of estrogen receptors and an inhibitor of human progesterone metabolizing enzyme AKR1C1 and fungal 17beta-hydroxysteroid dehydrogenase and a redox inhibitor (IC50=0.6 and 6.0 µM, respectively). 3,7-Dihydroxyflavone is a fluorescent binding substrate for human serum albumin (HSA) with excitation wavelengths of 370 nm (pH 7.4) and 350 nm (pH 3.5), respectively, and emission wavelength of 515 nm[1][2].
Molecular Weight:
254.24
Purity:
98.04
CAS Number:
[492-00-2]
Formula:
C15H10O4
Target:
17beta-HSD,Aldose Reductase,Estrogen Receptor/ERR
Application Notes:
MCE Product type: Natural Products
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