Ganciclovir triphosphate (GCV-TP) disodium is a synthetic 2-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate disodium is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate disodium has an IC50 of 0.01 µM against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate disodium has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition[1].
Molecular Weight:
541.15
Purity:
98.65
Formula:
C9H16N5Na2O13P3
Target:
CMV,DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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