Hdm2 E3 ligase inhibitor 1, CAS [[414905-09-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-131667
Supplier Catalog Number:
HY-131667
Alternative Catalog Number:
MCE-HY-131667-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Hdm2 E3 ligase inhibitor 1 (Compound 1) is a reversible inhibitor for Hdm2 (an E3 ubiquitin ligase)-mediated ubiquitination of the p53 protein with an IC50 of 12.7 µM. Hdm2 E3 ligase inhibitor 1 binds Hdm2, blocks Hdm2-catalyzed ubiquitin transfer from preligated Ub-Ubc4 to p53, inhibits p53 ubiquitination, stabilizes p53 protein in tumor cell and exhibits antitumor efficacy[1].
Molecular Weight:
350.24
CAS Number:
[414905-09-2]
Formula:
C10H8F6N2O3S
Target:
E1/E2/E3 Enzyme,MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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