Thalidomide-NH-CH2-COOH TFA is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-CH2-COOH TFA can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937)[1].
Molecular Weight:
445.30
CAS Number:
[2377032-39-6]
Formula:
C17H14F3N3O8
Target:
Apoptosis,Autophagy,Ligands for E3 Ligase
Application Notes:
MCE Product type: Reference compound
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