Pregnenolone 16alpha-carbonitrile is an orally active prototypical and effective rodent-PXR activator. Pregnenolone 16alpha-carbonitrile, a synthetic steroid, induces cytochrome P450 3A expression. Pregnenolone 16alpha-carbonitrile exhibits increased resistance to subsequent stressful insults[1][2][3].
Molecular Weight:
341.49
Purity:
98.48
CAS Number:
[1434-54-4]
Formula:
C22H31NO2
Target:
Cytochrome P450,Pregnane X Receptor (PXR)
Application Notes:
MCE Product type: Reference compound
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