JHU37160 is a potent and brain-penetrant DREADD agonist, with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue[1].
Molecular Weight:
358.84
Purity:
99.98
CAS Number:
[2369979-68-8]
Formula:
C19H20ClFN4
Target:
mAChR
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted