JHU37152 is a potent and brain-penetrant DREADD agonist, with EC50s of 5 nM and 0.5 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37152 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue[1].
Molecular Weight:
358.84
Purity:
99.45
CAS Number:
[2369979-67-7]
Formula:
C19H20ClFN4
Target:
mAChR
Application Notes:
MCE Product type: Reference compound
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