JAK2-IN-7 is a selective JAK2 inhibitor with IC50s of 3, 11.7, and 41 nM for JAK2, SET-2, and Ba/F3V617F cells, respectively. JAK2-IN-7 possesses >14-fold selectivity over JAK1, JAK3, FLT3. JAK2-IN-7 stimulates cell cycle arrest in the G0/G1 phase and induces tumor cellapoptosis. Antitumor activities[1].
Molecular Weight:
459.59
Purity:
99.15
CAS Number:
[2593402-36-7]
Formula:
C26H33N7O
Target:
Apoptosis,FLT3,JAK
Application Notes:
MCE Product type: Reference compound
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