3-Chlorodiphenylamine is a high affinity Ca2+ sensitizer of cardiac muscle. 3-Chlorodiphenylamine is based on diphenylamine and binds to the isolated N-domain of cardiac troponin C (cTnC) (Kd=6 µM). 3-Chlorodiphenylamine is an excellent starting scaffold for the development of more potent Ca2+-sensitizing compounds due to its small size, and can be used for systolic heart failure research[1].
Molecular Weight:
203.67
Purity:
98.74
CAS Number:
[101-17-7]
Formula:
C12H10ClN
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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