LASSBio-1135 (Compound 3a) is an orally active TRPV1 antagonist. LASSBio-1135 is an anti-inflammatory and analgesic compound. LASSBio-1135 inhibits moderately the human PGHS-2 enzyme activity (IC50 = 18.5 µM). LASSBio-1135 reverts the Capsaicin (HY-10448)-induced thermal hyperalgesia and reduces the carrageenan-induced rat paw edem[1].
Molecular Weight:
286.33
Purity:
99.05
CAS Number:
[852453-71-5]
Formula:
C18H14N4
Target:
TRP Channel
Application Notes:
MCE Product type: Reference compound
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