NVP-TAE 226 (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. NVP-TAE 226 (TAE226) also effectively inhibits Pyk2 and insulin receptor (InsR) with IC50s of 3.5 nM and 44 nM, respectively[1][2].
Molecular Weight:
468.94
Purity:
99.77
CAS Number:
[761437-28-9]
Formula:
C23H25ClN6O3
Target:
Apoptosis,FAK,IGF-1R,Insulin Receptor,Pyk2
Application Notes:
MCE Product type: Reference compound
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