(1E)-CFI-400437 (dihydrochloride), CAS [[1247000-76-5]]

Product Overview

• Article Name: (1E)-CFI-400437 (dihydrochloride), CAS [[1247000-76-5]]
• Biozol Catalog Number: MCE-HY-132135
• Supplier Catalog Number: HY-132135
• Alternative Catalog Number: MCE-HY-132135-50MG,MCE-HY-132135-100MG,MCE-HY-132135-25MG,MCE-HY-132135-10MMX1ML,MCE-HY-132135-10MG,MCE-HY-132135-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

(1E)-CFI-400437 dihydrochloride is a potent PLK4 (IC50= 0.6 nM) inhibitor and selective against other members of the PLK family (>10 µM). (1E)-CFI-400437 dihydrochloride inhibits Aurora A, Aurora B, KDR and FLT-3 with IC50s of 0.37, 0.21, 0.48, and 0.18 µM, respectively. Antiproliferative activity[1].

Product Properties

• Molecular Weight: 565.49
• Purity: 98.08
• CAS Number: [1247000-76-5]
• Formula: C29H30Cl2N6O2
• Target: Polo-like Kinase (PLK)

Application Notes

• Application Notes: Reference compound