Velzatinib (M4205) is a multi-target inhibitor for PDGFRB, PDGFRA, CSF1R, c-Kit, FLT3, and LCK, with an IC50s of 2.6, 50, 5.5, 44, 141 and 141 nM, respectively. Velzatinib exhibits antitumor efficacy in xenograft mouse models[1].
Molecular Weight:
508.62
Purity:
99.47
CAS Number:
[2590556-80-0]
Formula:
C29H32N8O
Target:
c-Fms,c-Kit,FLT3,PDGFR,Src
Application Notes:
MCE Product type: Reference compound
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