PD-1/PD-L1-IN-9 is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 can enhance the killing activity of tumor cells by immune cells. PD-1/PD-L1-IN-9 also exhibits significant in vivo antitumor activity in a CT26 mouse model[1].
Molecular Weight:
348.44
Purity:
99.59
CAS Number:
[2628506-54-5]
Formula:
C22H24N2O2
Target:
PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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