DS45500853 is an estrogen-related receptor alpha (ERRalpha) agonist. DS45500853 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRalpha ligand-binding domain (LBD, 1.2 µM) with an IC50 value of 0.80 µM. DS45500853 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM)[1].
Molecular Weight:
284.35
Purity:
99.18
CAS Number:
[2735803-28-6]
Formula:
C18H20O3
Target:
Estrogen Receptor/ERR
Application Notes:
MCE Product type: Reference compound
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