Mirvetuximab soravtansine (solution), CAS [[1453084-37-1]]
Biozol Catalog Number:
MCE-HY-132258A
Supplier Catalog Number:
HY-132258A
Alternative Catalog Number:
MCE-HY-132258A-1MG,MCE-HY-132258A-5MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
IMGN853 (solution)
Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor alpha (FRalpha) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A, and the drug-linker conjugate for ADC is sulfo-SPDB-DM4 (HY-101141). Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage[1].
Molecular Weight:
150000 (average)
Purity:
98.20
CAS Number:
[1453084-37-1]
Formula:
C6482H10006N1714O2022S44(C42H58ClN3O14S3)n
Target:
Antibody-Drug Conjugates (ADCs),Antifolate
Application Notes:
MCE Product type: Reference compound
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