Rivanicline (RJR-2403) hemioxalate is a neuronal nicotinic receptor agonist. Rivanicline hemioxalate is highly selective for the rat brain cortex nAChRs (Ki = 26 nM, EC50 of 732 nM) and alpha4beta2 subtype (Ki = 26 nM, EC50 = 16 µM). Rivanicline hemioxalate can significantly restore the learning impairment and cognitive dysfunction. Rivanicline hemioxalate can be used for the study of neurodegenerative diseases (such as schizophrenia or Alzheimers disease)[1][2][3][4][5].
Molecular Weight:
207.23
Purity:
95
Formula:
C11H15N2O2
Target:
nAChR
Application Notes:
MCE Product type: Reference compound
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