Hu7691 free base is an orally active, selective Akt inhibitor with IC50s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively. Hu7691 free base inhibits tumor growth and enables decrease of cutaneous toxicity in mice[1].
Molecular Weight:
414.42
CAS Number:
[2241232-43-7]
Formula:
C22H21F3N4O
Target:
Akt,PKA,PKC,Ribosomal S6 Kinase (RSK),ROCK,SGK
Application Notes:
MCE Product type: Reference compound1
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