(1S,4R)-CC-90005 is the (1S,4R)-enantiomer of CC-90005 (HY-132304). CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-theta (PKC-theta), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-theta over PKC-delta (IC50 = 4440 nM). CC-90005 can inhibit T cell activation by inhibiting IL-2 expression[1].
Molecular Weight:
447.48
Purity:
99.95
Formula:
C21H27F2N7O2
Target:
PKC
Application Notes:
MCE Product type: Reference compound
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