VEGFR-3-IN-1 is a potent and selective VEGFR3 inhibitor with an IC50 of 110.4 nM. VEGFR-3-IN-1 significantly inhibits proliferation and migration of VEGF-C-induced human dermal lymphatic endothelial cells (HDLEC), MDA-MB-231, and MDA-MB-436 cells by inactivating the VEGFR3 signaling pathway, and also effectively inhibits breast cancer growth[1].
Molecular Weight:
616.10
Purity:
98.76
CAS Number:
[2756668-73-0]
Formula:
C29H29ClF3N7OS
Target:
VEGFR
Application Notes:
MCE Product type: Reference compound
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