Talabostat (Val-boroPro, PT100) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC50 Ki = 0.18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM), inhibits DPP8/9 (IC50 = 4/11 nM, Ki = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC50 = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities[1][2][3].
Molecular Weight:
214.07
CAS Number:
[149682-77-9]
Formula:
C9H19BN2O3
Target:
Dipeptidyl Peptidase
Application Notes:
MCE Product type: Reference compound
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