Dolutegravir (sodium), CAS [[1051375-19-9]]

Product Overview

• Article Name: Dolutegravir (sodium), CAS [[1051375-19-9]]
• Biozol Catalog Number: MCE-HY-13238A
• Supplier Catalog Number: HY-13238A
• Alternative Catalog Number: MCE-HY-13238A-10MG,MCE-HY-13238A-25MG,MCE-HY-13238A-5MG,MCE-HY-13238A-50MG,MCE-HY-13238A-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: S/GSK1349572 (sodium)

Product Description

Dolutegravir sodium (S/GSK1349572 sodium) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir sodium (S/GSK1349572 sodium) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir sodium (S/GSK1349572 sodium) retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM)[1][2].

Product Properties

• Molecular Weight: 441.36
• Purity: 99.97
• CAS Number: [1051375-19-9]
• Formula: C20H18F2N3NaO5
• Target: HIV,HIV Integrase

Application Notes

• Application Notes: MCE Product type: Reference compound1