Dolutegravir-d5, CAS [[2249814-82-0]] Preis auf Anfrage

Catalog Number: MCE-HY-13238S2
Article Name: Dolutegravir-d5, CAS [[2249814-82-0]] Preis auf Anfrage
Biozol Catalog Number: MCE-HY-13238S2
Supplier Catalog Number: HY-13238S2
Alternative Catalog Number: MCE-HY-13238S2-1MG,MCE-HY-13238S2-500UG
Manufacturer: MedchemExpress
Category: Biochemikalien
Alternative Names: S/GSK1349572-d5
Dolutegravir-d5 is deuterium labeled Dolutegravir. Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM)[1][2].
Molecular Weight: 424.41
CAS Number: [2249814-82-0]
Formula: C20H14D5F2N3O5
Target: HIV,HIV Integrase,Isotope-Labeled Compounds
Application Notes: MCE Product type: Isotope-Labeled Compounds