Apitolisib (GDC-0980, GNE 390, RG 7422) is a selective, potent, orally bioavailable Class I PI3 kinase and mTOR kinase (TORC1/2) inhibitor with IC50s of 5 nM/27 nM/7 nM/14 nM for PI3Kalpha/PI3Kbeta/PI3Kdelta/PI3Kgamma, and with a Ki of 17 nM for mTOR.
Molecular Weight:
498.60
Purity:
99.29
CAS Number:
[1032754-93-0]
Formula:
C23H30N8O3S
Target:
Apoptosis,mTOR,PI3K
Application Notes:
MCE Product type: Reference compound
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