Givosiran, CAS [[1639325-43-1]]

Product Overview

• Article Name: Givosiran, CAS [[1639325-43-1]]
• Biozol Catalog Number: MCE-HY-132610
• Supplier Catalog Number: HY-132610
• Alternative Catalog Number: MCE-HY-132610-10MG,MCE-HY-132610-5MG,MCE-HY-132610-1MG,MCE-HY-132610-100MG,MCE-HY-132610-50MG,MCE-HY-132610-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: ALN-AS1

Product Description

Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic delta-aminolevulinic acid (ALA) and porphobilinogen (PBG) levels. Givosiran demonstrates potent inhibitory activity against ALAS1 in mouse, rat, and cynomolgus monkey models. Givosiran can be used for the research of acute hepatic porphyria (AHP)[1][2].

Product Properties

• Molecular Weight: 16300.60
• Purity: 98.51
• CAS Number: [1639325-43-1]
• Formula: C524H694F16N173O316P43S6
• Target: Small Interfering RNA (siRNA)

Application Notes

• Application Notes: Oligonucleotides