PIK-75 hydrochloride is a reversible DNA-PK and p110alpha-selective inhibitor, which inhibits DNA-PK, p110alpha and p110gamma with IC50s of 2, 5.8 and 76 nM, respectively. PIK-75 hydrochloride inhibits p110alpha >200-fold more potently than p110beta (IC50=1.3 µM)[1][2]. PIK-75 hydrochloride induces apoptosis[3].
Molecular Weight:
488.74
Purity:
99.66
CAS Number:
[372196-77-5]
Formula:
C16H15BrClN5O4S
Target:
Apoptosis,DNA-PK,PI3K
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
