Nepicastat (SYN117) is a selective, potent, and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat (SYN117) produces concentration-dependent inhibition of bovine (IC50=8.5 nM) and human (IC50=9 nM) dopamine-beta-hydroxylase. Nepicastat (SYN117) can cross the blood-brain barrier (BBB)[1][2][3].
Molecular Weight:
295.35
CAS Number:
[173997-05-2]
Formula:
C14H15F2N3S
Target:
Dopamine beta-hydroxylase
Application Notes:
MCE Product type: Reference compound
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