EEDi-5273 (APG-5918) is a potent and orally active embryonic ectoderm development (EED) inhibitor with an IC50 of 0.2 nM. EEDi-5273 can inhibit the polycomb repressive complex 2 (PRC2) activity and block trimethylation of histone H3 lysine 27. EEDi-5273 can be used for the research of cancer, such as ovarian cancer[1].
Molecular Weight:
526.49
Purity:
99.09
CAS Number:
[2585648-55-9]
Formula:
C26H22F4N6O2
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound1
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