Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 µM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-kappaB-dependent inflammatory responses by directly targeting IkappaB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders[1][2][3].
Molecular Weight:
350.45
Purity:
99.87
CAS Number:
[42971-09-5]
Formula:
C22H26N2O2
Target:
IKK,Phosphodiesterase (PDE),Sodium Channel
Application Notes:
MCE Product type: Natural Products
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