MK-8033 is an orally active ATP competitive c-Met/Ron dual inhibitor (IC50s: 1 nM (c-Met),7 nM (Ron)), with preferential binding to the activated kinase conformation. MK-8033 can be used in the research of cancers, such as breast and bladder cancers, non-small cell lung cancers (NSCLCs)[1][2].
Molecular Weight:
471.53
Purity:
98.34
CAS Number:
[1001917-37-8]
Formula:
C25H21N5O3S
Target:
c-Met/HGFR
Application Notes:
MCE Product type: Reference compound
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