SAR439859 (compound 43d) is an orally active, non-steroidal, and selective estrogen receptor degrader (SERD). SAR439859 is an effective ER antagonist with ER degradation activity, an EC50 of 0.2 nM. SAR439859 can show potent anti-tumor effects and limited cross-resistance in ER+ breast cancer.
Molecular Weight:
554.48
Purity:
99.79
CAS Number:
[2114339-57-8]
Formula:
C31H30Cl2FNO3
Target:
Estrogen Receptor/ERR
Application Notes:
MCE Product type: Reference compound
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