VHL Ligand 8, CAS [[2701565-76-4]]

Product Overview

• Article Name: VHL Ligand 8, CAS [[2701565-76-4]]
• Biozol Catalog Number: MCE-HY-133045
• Supplier Catalog Number: HY-133045
• Alternative Catalog Number: MCE-HY-133045-5MG,MCE-HY-133045-25MG,MCE-HY-133045-50MG,MCE-HY-133045-10MG,MCE-HY-133045-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

VHL Ligand 8 is a VHL ligand. VHL Ligand 8 can be used to synthesize ARD-266 (HY-133020), a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. ARD-266 effectively induces degradation of AR protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0.2-1 nM[1].

Product Properties

• Molecular Weight: 443.49
• Purity: 98.04
• CAS Number: [2701565-76-4]
• Formula: C23H29N3O6
• Target: Ligands for E3 Ligase

Application Notes

• Application Notes: MCE Product type: Reference compound