FM26 (compound 25) is a potent and allosteric retinoic acid receptor-related orphan receptor gammat (RORgammat) inverse agonists with an IC50 of 264 nM. FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells[1].
Molecular Weight:
461.82
CAS Number:
[2407981-35-3]
Formula:
C22H15ClF3N3O3
Target:
ROR
Application Notes:
MCE Product type: Reference compound
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