IIIM-1266 is a NLRP3 inflammasome inhibitor. IIIM-1266 inhibits IL-1beta release in mouse macrophages (J774A.1 cells) (IC50 = 2.3 µM) and significantly reduced the protein expression level of mature IL-1beta. IIIM-1266 can be used for the study of inflammation[1].
Molecular Weight:
306.38
CAS Number:
[2468202-93-7]
Formula:
C15H18N2O3S
Target:
Interleukin Related,NOD-like Receptor (NLR)
Application Notes:
MCE Product type: Reference compound
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