YW1128 (compound 3a) is a potent Wnt/beta-Catenin inhibitor. YW1128 induces the proteasome degradation of beta-catenin and subsequent inhibits the Wnt/beta-catenin signaling in cells. YW1128 significantly decreases hepatic lipid accumulation. YW1128 improves glucose tolerance of high fat diet-fed mice without noticeable toxicity. YW1128 down regulates the genes involved in the glucose and fatty acid anabolism[1].
Molecular Weight:
343.38
Purity:
99.38
CAS Number:
[2131223-64-6]
Formula:
C20H17N5O
Target:
Wnt,beta-catenin
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
