CX-5461 (Standard) is the analytical standard of CX-5461. This product is intended for research and analytical applications. CX-5461 is a potent and oral rRNA synthesis inhibitor. It inhibits RNA polymerase I-driven transcription of rRNA with IC50s of 142, 113, and 54 nM in HCT-116, A375, and MIA PaCa-2 cells, respectively[1].
Molecular Weight:
513.61
CAS Number:
[1138549-36-6]
Formula:
C27H27N7O2S
Target:
DNA/RNA Synthesis,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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