WF-47-JS03 is a potent, selective and brain-penetrantRET kinase inhibitor with IC50s of 1.7 nM and 5.3 nM for KIF5B-RET transfected Ba/F3 cells and CCDC6-RET transfected LC-2/ad lung cancer cells, respectively. WF-47-JS03 demonstrates >500-fold selectivity against kinase insert domain receptor (KDR)[1].
Molecular Weight:
514.66
Purity:
99.63
CAS Number:
[2561413-77-0]
Formula:
C30H38N6O2
Target:
RET
Application Notes:
MCE Product type: Reference compound
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